Scientific References

Clinical & Regulatory Citations

Key publications, regulatory guidance, and technical documentation underpinning the CareFuse platform and application stories.

1

HL7 Da Vinci PAS Implementation Guide.

Da Vinci PAS (FHIR IG)
2

Harvard Health Publishing. How long will my hip or knee replacement last?

Harvard Health (2018)
3

Renub Research. Knee replacement market analysis and forecast.

Renub Research
4

ScienceDirect. Economic burden of knee and hip arthroplasty in younger patients.

ScienceDirect (2025)
5

ScienceDirect. Dissatisfaction rates following total knee arthroplasty.

ScienceDirect (2017)
6

Centers for Medicare & Medicaid Services. THA/TKA patient-reported outcomes measure requirements.

CMS THA/TKA PRO-PM
7

Evidence on variation and subjectivity in TKA decision-making.

BMC Health Serv Res (2008) Clin Orthop Relat Res (2013)
8

Cooley LLP. State artificial intelligence regulation tracker and analysis (2025).

Cooley State AI Regulation Analysis
9

Structured conservative care effectiveness and payer budget impact modeling for knee osteoarthritis.

Arthritis Care & Research Budget Impact Analysis
10

Clement ND, et al. WOMAC MCID ≈ 10 at 12 months post-TKA.

PubMed (PMID 30179956) PMC6259858
11

Papakostidis C, Giannoudis PV, Watson JT, et al. Serious adverse events and 30-day readmission following elective TKA.

PubMed (PMID 33789702) PMC8011390
12

CMS Interoperability & Prior Authorization Final Rule (CMS-0057-F) fact sheet.

CMS Fact Sheet (PDF)
13

NAIC Model Bulletin on Artificial Intelligence Systems.

NAIC AI Model Bulletin (PDF)
14

Medical Board of California. AB-3030 generative AI patient communication notice.

Medical Board of California - GenAI Notification
15

UpToDate. Total knee arthroplasty: Outcomes and indications.

UpToDate – TKA Outcomes
16

Nature npj Digital Medicine. Identifying patients unlikely to benefit from total knee arthroplasty using ML.

npj Digital Medicine (2024)
17

CMS. Advancing Interoperability and Improving Prior Authorization Processes Final Rule fact sheet.

CMS Prior Authorization Final Rule (2024)
18

AAOS / CMS. PRO-PM Frequently Asked Questions fact sheet (PROMs collection guidance for hip & knee arthroplasty).

PRO-PM FAQ Fact Sheet (PDF)
19

CMS Comprehensive Care for Joint Replacement (CJR) Model.

CMS CJR Model Overview
20

Wilding JPH, et al. Once-weekly semaglutide in adults with overweight or obesity.

NEJM (2021)
21

Farr JN, et al. Effect of semaglutide on knee pain in obese adults with osteoarthritis.

JAMA (2023)
22

Lundberg SM, Lee SI. SHAP (SHapley Additive exPlanations) GitHub repository.

SHAP GitHub
23

Vickers AJ, Elkin EB. Decision curve analysis: A novel method for evaluating prediction models.

Medical Decision Making (2008)
24

Healthcare Cost and Utilization Project. Statistical Brief #210: Characteristics of Inpatient Stays Involving Total Knee Arthroplasty, 2015.

HCUP Statistical Brief #210
25

Healthcare Cost and Utilization Project. Statistical Brief #211: 30-Day Readmissions Following Hospitalization for Total Knee Replacement, 2009–2014.

HCUP Statistical Brief #211
26

Agency for Healthcare Research and Quality. Economic burden of revision total knee arthroplasty in the United States.

AHRQ Revision TKA Cost Analysis
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